I'm a big fan of guitar-based rock music. Jason Becker is one of the best of this genre. Actually he's more than one of the best. Check out this, rather humbling, video of a man plucked from his prime but still going.

He contracted(?) Amyotrophic Lateral Sclerosis, a body wasting disease just after he started working with David Lee Roth (as Steve Vai's replacement). I wouldn't wish ALS on anyone...